2024 Pilot & Feasibility Grant Awardees
Current Awardees
Edward Li MD, PhDSingle-Cell and Spatial Transcriptomic Dissection of Inflammatory Hair Loss Disorders
PI: Edward Li MD, PhD, Postdoctoral Fellow of Dermatology
Colby S Thaxton, MD, PhDHigh-Density Lipoprotein Receptor Expression and Targeting in Inflammatory Skin Disease
High-Density Lipoprotein Receptor Expression and Targeting in Inflammatory Skin Disease
William A Muller, MD, PhDSpatiotemporal Dissection of Dermal Inflammation and Therapeutic Intervention Through High-Resolution, Long-Term Intravital Imaging
PI: William A Muller, MD, PhD, Janardan K. Reddy, MD Professor of Pathology (Experimental Pathology, Autopsy)
Aim 1: Intravital imaging of acute and chronic dermal inflammation
A. Determine optimal parameters for multiphoton imaging of sterile inflammation in the ear skin.
B. Determine how anti-inflammatory therapy affects the natural history of sterile inflammation.
Aim 2: Intravital imaging of the development and progression of psoriasis in the ear skin.
A. Determine the spatiotemporal parameters of inflammation in the Imiquimod model of psoriasis.
B. Determine how selected anti-inflammatory agents affect the natural history of psoriasis.